Cleveland Star
ClevelandStar.com Friday 12th March 2010 Edition 071/8
bullet Navigation corner
bullet Cleveland News
bullet Ohio State News
bullet National News
bullet World News
bullet Business News
bullet RSS Directory rss

bullet Market Indices corner
DJIA graph
DJI: 44.51 10611.8 0.42%
FTSE: 1.40 5615.86 0.02%
NAS: 9.51 2368.46 0.40%
Nikkei: 86.31 10751.3 0.81%

bullet Quotable Quotes corner
"The idea of human rights begins with a fundamental commitment to the dignity that is the birthright of every man, woman and child."
Hillary Rodham Clinton
The U.S. Secretary of State was speaking on the release of the 2009 Country Reports on Human Rights Practices.

bullet Exchange Rates corner
$£€ United States, Dollar Euro Canada, Dollar Japan, Yen United Kingdom, Pound
United States, Dollar - 0.725 1.022 90.40 0.659
Euro 1.377 - 1.408 124.5 0.908
Canada, Dollar 0.978 0.710 - 88.43 0.645
Japan, Yen 0.011 0.008 0.011 - 0.007
United Kingdom, Pound 1.515 1.100 1.549 137.0 -

bullet More Cleveland News corner
<h1>female Rabbis Find Field Still Not Level</h1>
<h1>mumps Shots Only ‘precautionary,’ Says Doctor</h1>
<h1>fms’s New Building: A Sneak Peek</h1>
<h1>survivor Tells Story In War Came To Me</h1>

bullet State News corner
Ohio Learning Network Renews Centss Online Audit Tool License To Further Improve Online Student Services
Osu, Columbus State Could Touch Cooper Stadium Race Track

bullet National News corner
Billy Corgan blasts John Mayer over Jessica Simpson comments
Porn star says 'Bachelor' castoff Rozyln Papa did not star in sex tape
NY woman awarded $3.5m after doc gives her 'four boobs'
Director of Fugees video 'Killing Me Softly' impregnated daughters
Tommy Hilfiger speaks out on why he hit Axl Rose
Brain tumour's 'grow-or-go' switch found

bullet Subscribe corner
Get Cleveland Star headlines sent daily.

bullet Add Headlines corner
Add Cleveland news headlines to your site.
Start here.
bullet Cleveland Star corner
Breaking News
Cleveland Cruises Past Shorecrest
THE ASSOCIATED PRESS TACOMA, Wash. -- Cheyenne Wilson had 20 points, Whitney Wilson added 19 points and 13 rebounds and Cleveland cruised past Shorecrest 65-52 in the quarterfinals of the...

Cleveland 65, Shorecrest 52.
By THE ASSOCIATED PRESS CLEVELAND (65) Scott 3, Trotter 2, McGee 0, Jenkins 12, C.Wilson 20, Savini 5, Smith 4, W.Wilson 19. Totals 24-54 14-23 65. SHORECREST (52) Axelson 5, Ruhlman 0, Schrote...
More breaking stories
World News
Talks with Taliban bolstered by Pakistan supportTalks with Taliban bolstered by Pakistan support
Afghanistan has praised Pakistan's offer to help mediate with the...

Gates says Gulf countries are worried about IranGates says Gulf countries are worried about Iran
U.S. Defense Secretary Robert M. Gates has met lkeaders in Saudi Arabia and the UAE to garner support for increasing sanctions against...
Christian and Muslim sites being ignored by Israel, says U.S. State DepartmentChristian and Muslim sites being ignored by Israel, says U.S. State Department
The U.S. State Department has scolded Israel for only recognizing Jewish holy...
More international stories
Business News
Lehman Brothers auditors were negilgent says reportLehman Brothers auditors were negilgent says report
Auditors, former executives, Barclays Bank, and Wall Street banks have copped a serve from a court-appointer examiner who probed the Lehman Brothers...

U.S. stocks recover in late tradingU.S. stocks recover in late trading
A surge in bank shares returned the major indices to the black Thursday, after rough sailing earlier in the...
Banks in Australia profiteering says regulatorBanks in Australia profiteering says regulator
Australia's biggest banks are gouging its customers, the Reserve Bank of Australia...
More business stories

bullet Early immune response may help combat hit-and-hide cancer viruses corner

Washington, Jan 16 : Retroviruses such as HIV and HTLV-1 don't hit-and-run, they hit-and-hide. Now, researchers at Ohio State University have revealed that an early and strong immune response might help curb the infection that is likely to last long.

According to the researchers, cancer viruses slip into host cells and insert their own DNA into the cell's DNA, and from this refuge they establish an infection that lasts a lifetime.

"Our findings indicate that if the immune system could respond strongly to HTLV-1 and kill infected target cells early, it may inhibit the virus's ability to establish reservoirs of infected cells and make the infection more manageable later," said principal investigator Michael Lairmore, a professor and chair of veterinary biosciences and a cancer researcher at OSUCCC-James.

"This study tells us that the more we know about the earliest events of infection, the more it will help us develop vaccines and might block those events," Lairemore added.

Lairmore and his colleagues examined HTLV-I infection in rabbits that were treated with the drug cyclosporin A, which is commonly used to suppress the immune system in people following organ transplantation.

They compared animals treated with this drug prior to viral infection with those given the drug one week after infection.

In animals given the immune-suppressing drug first, the virus flourished. The number of virus copies jumped to 200 per 10,000 immune cells (lymphocytes), compared with 40 per 10,000 immune cells in control animals (these were infected with the virus but not given the drug).

After a week or two, the number of virus copies fell, ranging from 113 to 160 for remainder of the 10-week experiment.

In the animals that were given the virus first and then the immune-suppressing drug a week later, on the other hand, the virus languished.

"The first experiment told us that if the immune system is suppressed, the viral load goes up - and we expected that," said Lairmore.

"The second group was the surprise. Their viral load was low from the start, and it stayed that way. We didn't expect that. We thought the virus would recover and come back up.

"Collectively, our findings indicate that the immune system plays a key role in controlling HTLV-1 spread during early infection, which has important implications for a vaccine against this virus and for therapy for HTLV-1-associated diseases," he added.


bullet Cleveland Star corner
The Cleveland Star is essentially a local Cleveland newspaper, but with a national and international perspective, designed to provide readers with a one-stop shop for Cleveland, national US, regional, and world news coverage, weather and sports information, with live updates on breaking business stories, and what's happening in the financial markets.

The biggest advantage we have is that we are an online newspaper, which means we are constantly refreshing our stories as more and more information comes to hand. Often when a story breaks the initial details are sketchy.

We and our sources around the world work hard to gather more information, verify facts, and provide a perspective of the major stories. Expert opinion often accompanies our articles to better inform readers, and provide a more complete understanding
of the news we deliver.

Financial markets and business reports are regular features as we pin down what's happening, and constantly refresh stock market indice readings, dollar currency rates, and breaking business news reports. Our world sports coverage is a priority, as is our regional news.

We like to think if you're looking for breaking news out of Cleveland, Ohio, the United States, or the world, you'll look for it first at the Cleveland Star.

bullet Feedback corner
  • Comments or suggestions for this site? Use our contact page.
  • Have your say. Post on our letters forum.
  • See what others say on our letters forum.
  • bullet Sponsored Links corner

    bullet Cleveland Weather corner
    Cleveland, Ohio
    Now 53.7°F/12.1°C Rain Showers
    Friday 58°F/14°C Rain Showers
    Saturday 47°F/8°C Rain Showers
    Sunday 43°F/6°C Rain Showers
    Monday 45°F/7°C Mostly Cloudy
    Tuesday 47°F/8°C Partly Cloudy

    Ohio State Weather

    bullet Movie Review corner

    bullet Travel corner
    British Airways' terror-accused employee wanted to go to Pakistan for training
    Gordon Brown voted worst male travel companion
    Switched On Media Engaged With Flight Centre, Escape Travel And Student Flights On Seo
    American Airlines: Paperless Passes At Lindbergh

    bullet Space corner
    MINI-ME to uncover secrets of outer layers of Earth's atmosphere
    NASA proposes mission to snatch a piece from 'time capsule' asteroid
    Lunar mirror mystery solved by scientists
    'Terminator asteroids' can regenerate after being nuked
    Meteorites could have kick-started life on earth 4 billion years ago

    bullet Record Your Vote corner
    Do you believe Gordon Brown will still be prime minister of the UK after the forthcoming elections?


    bullet Hotel Review corner
    Metro Hotel on Pitt
    Metro Hotel on Pitt

    A truly affordable hotel in Sydney, with stylish decor, great location and in-house snazzy brasserie? If the notion of...


    bullet Football corner
    Man Convicted In Slaying Of Broncos Cornerback
    Dan Snyder On Unusually Quiet Redskins: 'we've Got A Game Plan'
    Football Hall Of Famer, Tv Star Olsen Dies At 69
    Tomlinson Leaves Vikings, Headed To Jets
    Nfl Panel Finds Some Injuries More Common On Turf